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T1428
Sigma
apo-Transferrin bovine
≥98%, cell culture tested
| EC Number: | 234-318-8 |
| MDL number: | MFCD00130536 |
Description
| Application | All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco's Modified Eagle's Medium/Ham's Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred. |
Properties
| assay | ≥98% |
| total impurities | iron, essentially free |
| solubility | H2O: 50 mg/mL |
| suitability | cell culture tested |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
